Research Progress on Biomarkers of Phlegm-Heat and Bowel-Excess Syndrome in Stroke Based on Multiomics
- VernacularTitle:基于多组学的中风病痰热腑实证生物标志物研究进展
- Author:
Chenfei HE
1
;
Haoge CHENG
;
Chunlong RAN
;
Xiangzhe LIU
Author Information
- Publication Type:Journal Article
- Keywords: Stroke; Phlegm-Heat and Bowel-Excess Syndrome; Biomarkers; Research progress
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2024;26(10):2600-2606
- CountryChina
- Language:Chinese
- Abstract: Stroke is a disease that seriously threatens human health.Traditional Chinese medicine believes that turbid phlegm and sthenia fever are common pathological factors of stroke.The early diagnosis of stroke usually depends on advanced imaging techniques,such as MRI and CT,and there is still a lack of diagnostic biomarkers.Therefore,exploring the biological markers of Phlegm-Heat and Bowel-Excess Syndrome of stroke,combining macro-dialectics with micro-dialectics,can provide objective data support for the prevention and treatment of stroke by traditional Chinese medicine,which is of great significance for the diagnosis,treatment and prognosis evaluation of stroke.This paper reviews and summarizes the clinical biochemical indicators,microbiome,genomics,transcriptomics,proteomics,metabolomics and other aspects,aiming to find specific biomarkers related to Phlegm-Heat and Bowel-Excess Syndrome of stroke,so as to provide molecular basis for the objective research system of stroke"syndrome"and new ideas for the study of syndrome essence.
