Summary of the best evidence for cognitive function improvement in Alzheimer's disease patients
10.3760/cma.j.cn115682-20241202-06617
- VernacularTitle:阿尔茨海默病患者认知功能改善的最佳证据总结
- Author:
Yijin WANG
1
;
Yanxuan ZHANG
1
;
Ruihan LI
1
;
Li QI
1
;
Weixin ZHANG
1
;
Yin GAO
1
Author Information
1. 齐齐哈尔医学院护理学院，齐齐哈尔 161006
- Publication Type:Journal Article
- Keywords:
Alzheimer's disease;
Cognition;
Summary of evidence;
Evidence-based nursing
- From:
Chinese Journal of Modern Nursing
2025;31(30):4152-4158
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To retrieve and summarize the best evidence for cognitive function improvement in Alzheimer's disease patients, so as to provide reference for clinical practice.Methods:Following the "6S" evidence model, guidelines, expert consensus, clinical decision, and systematic reviews on cognitive function improvement in Alzheimer's disease patients were systematically retrieved from domestic and foreign databases and websites. The search keywords included "Alzheimer's disease, cognitive function, improvement". Evidence-based nursing methods were used to evaluate the quality of literature and extract evidence. The search period was from July 1, 2000 to July 31, 2024.Results:A total of 15 articles were included, including five guidelines, four expert consensus, two clinical decision, and four systematic reviews. Sixteen pieces of best evidence were summarized from four aspects of evaluation and identification, pharmacological intervention, non-pharmacological intervention, and caregiver support.Conclusions:Patients with Alzheimer's disease require timely identification of symptoms related to cognitive impairment and assessment using standardized scales. Multiple intervention methods, such as pharmacological intervention, non-pharmacological intervention, and caregiver support, should be used to enhance patients' quality of life. Evidence application should be tailored to each patient's specific circumstances through individualized selection and adjustment to ensure the effectiveness and scientific rigor of cognitive function improvement strategies, thereby facilitating the translation of optimal evidence into clinical practice.
