Applications and advances of lipidomics in kidney disease
10.3969/j.issn.1006-5725.2025.01.001
- VernacularTitle:脂质组学在肾脏疾病中的应用与进展
- Author:
Jiahui WANG
1
;
Ke ZHENG
1
;
Xuemei LI
1
Author Information
1. 中国医学科学院北京协和医院肾内科(北京 100730)
- Publication Type:Journal Article
- Keywords:
diabetic nephropathy;
chronic kidney disease;
acute kidney injury;
lipidomics;
bio-markers;
pathogenesis
- From:
The Journal of Practical Medicine
2025;41(1):1-6
- CountryChina
- Language:Chinese
-
Abstract:
Kidney disease constitutes a significant global public health issue,with its associated healthcare burden escalating annually.Lipid metabolism disorders play a crucial role in the onset and progression of various kidney diseases.Given the diversity of lipid species and the complexity of metabolic pathways,traditional research methods often fall short in fully elucidating the intricate roles of lipids in kidney diseases.In this context,lipido-mics,the systematic analysis of lipid molecules and their metabolic alterations in biological samples,emerges as a powerful tool with unique research value and clinical potential.This review summarizes the latest findings in lipido-mics across various kidney diseases and discusses the challenges encountered in clinical application and future research directions.
