Research progress on colorectal alpha-fetoprotein-producing carcinoma
10.13315/j.cnki.cjcep.2025.10.016
- VernacularTitle:结直肠产甲胎蛋白癌的研究进展
- Author:
Xinwen ZHANG
1
;
Yuqing CHENG
Author Information
1. 江苏大学附属金坛医院/常州市金坛第一人民医院病理科,常州 213200
- Publication Type:Journal Article
- Keywords:
colorectal neoplasms;
hepatoid adenocarcinoma;
alpha-fetoprotein;
prognosis;
literature review
- From:
Chinese Journal of Clinical and Experimental Pathology
2025;41(10):1364-1368
- CountryChina
- Language:Chinese
-
Abstract:
Alpha-fetoprotein-producing carcinoma(AFPC)is a rare and highly aggressive tumor that may arise in various organs,including the gastrointestinal tract,pancreas,ovary,lung,gallbladder,uterus,and urological system.To date,most clinical studies have focused on gastric AFPC,which was characterized by deep invasion and high rate of lymph node and liver metastasis.In contrast,only a few studies have investigated colorectal AFPC,and these findings suggested that colorectal AFPC exhibits distinct clinicopathological features compared with conventional colorectal carci-noma.This review summarized the clinicopathological characteristics and recent research progress of colorectal AFPC,with the aim of improving the recognition and understanding of this entity among clinicians or pathologists.
