Advancements and future directions for differentiating multiple primary from me-tastatic esophageal squamous cell carcinoma
10.13315/j.cnki.cjcep.2025.10.001
- VernacularTitle:食管鳞状细胞癌多原发与转移的鉴别诊断研究进展与展望
- Author:
Nan YAO
1
;
Lei GUO
1
;
Liyan XUE
1
;
Weihua LI
1
Author Information
1. 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院病理科,北京 100021
- Publication Type:Journal Article
- Keywords:
esophageal neoplasms;
squamous cell carcinoma;
multifocal;
multiple primary;
metastasis;
differential diagnosis
- From:
Chinese Journal of Clinical and Experimental Pathology
2025;41(10):1261-1264,1272
- CountryChina
- Language:Chinese
-
Abstract:
Esophageal squamous cell carcinoma(ESCC)often exhibits a high incidence of multifocality.The dis-tinction between multiple primary and metastatic tumor origin is a prerequisite for precise diagnosis and treatment.Based on histopathological diagnosis,molecular pathological diagnostic indicators and technologies utilizing multi-omics approaches(DNA,RNA,protein)have been gradually identified.This article systematically reviews recent advance-ments in pathological diagnostic techniques for distinguishing the origin of multifocal ESCC and provides future perspec-tives,aiming to offer references for precise diagnosis.
