To Explore the Effect of Gut Microbiota-Bile Acid Axis on Insulin Resistance in Type 2 Diabetes Mellitus Based on Liver-Oriented Therapy with Qi Colligation Regulation
10.11842/wst.20240104004
- VernacularTitle:基于从肝论治的气络调节探讨肠道菌群-胆汁酸轴改善2型糖尿病胰岛素抵抗
- Author:
Yu WANG
1
;
Jiayuan SONG
;
Li WANG
;
Naiwen ZHANG
;
Chunli PIAO
Author Information
1. 长春中医药大学中医学院 长春 130000
- Publication Type:Journal Article
- Keywords:
Intestinal flora disorder;
Insulin resistance;
Type 2 diabetes mellitus;
Bile acid metabolism;
Qi collaterals theory
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2024;26(11):2914-2920
- CountryChina
- Language:Chinese
-
Abstract:
Studies have found that gut microbiota and bile acids metabolism play an important role in the occurrence and development of type 2 diabetes mellitus and insulin resistance(T2DM-IR).Recent studies have shown that the abnormal transformation of qi and Liver-qi collaterals caused by liver dysfunction is the key to the pathogenesis of T2DM-IR,which is closely related to intestinal flora and bile acid metabolism disorders.This article delves into the crucial role of intestinal microbiota and bile acid metabolism in regulating qi and collaterals within traditional Chinese medicine treatment from a hepatic perspective.It unveils its favorable impact on enhancing insulin sensitivity and achieving balance in energy metabolism,thereby offering valuable references for clinical management of T2DM.
