Progress of Proteomics Application in Gastric Cancer
10.3969/j.issn.1008-7125.2025.03.006
- VernacularTitle:蛋白质组学在胃癌中的应用进展
- Author:
Changyue ZHOU
1
;
Wenying YAN
1
;
Weichang CHEN
1
Author Information
1. 苏州大学附属第一医院消化内科(215006)
- Publication Type:Journal Article
- Keywords:
Stomach Neoplasms;
Proteomics;
Biological Markers;
Therapeutic Targets
- From:
Chinese Journal of Gastroenterology
2025;30(3):177-182
- CountryChina
- Language:Chinese
-
Abstract:
Gastric cancer is one of the most common malignant tumors of the digestive tract worldwide,and its early diagnosis and treatment have always been the focus of clinical research.In recent years,the rapid progress and wide application of proteomics technology have opened up a new perspective for the early screening,diagnosis,prognosis assessment,and mechanism exploration of gastric cancer.With the rapid development of bioinformatics,a series of innovative methods and cutting-edge results based on proteomics related to gastric cancer have emerged.This article reviewed the application progress of proteomics in gastric cancer from three dimensions:experimental techniques,analysis strategies,and major achievements,and discussed the challenges and opportunities in this field.In the future,with the integration of technologies and the deepening of interdisciplinary research,proteomics of gastric cancer is expected to make more breakthroughs,achieve clinical transformation,and provide more precise diagnosis and treatment plans for patients.