Imaging findings of pediatric atypical teratoid/rhabdoid tumor in the central nervous system
10.3969/j.issn.1002-1671.2025.11.021
- VernacularTitle:儿童中枢神经系统非典型畸胎瘤样/横纹肌样瘤影像学表现
- Author:
Ting GUI
1
;
Hui ZHENG
1
;
Jinning LI
1
;
Caiting CHU
1
;
Ming LIU
1
;
Yuzhen ZHANG
1
;
Yuhua LI
1
;
Dengbin WANG
1
Author Information
1. 上海交通大学医学院附属新华医院放射科,上海 200092
- Publication Type:Journal Article
- Keywords:
children;
atypical teratoid/rhabdoid tumor;
magnetic resonance imaging
- From:
Journal of Practical Radiology
2025;41(11):1857-1860
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the imaging findings of atypical teratoid/rhabdoid tumor(AT/RT)in the central nervous sys-tem of children and to improve the understanding of this disease.Methods A retrospective analysis was conducted on the imaging data of 55 children with AT/RT confirmed by pathology.Results Among the 55 AT/RT children,74.5％were under 3 years old,with a male-to-female ratio of 1.5∶1.Intracranial AT/RT appeared hyperdense or slightly hyperdense on CT scans and accompa-nied by calcification or hemorrhage occasionally.32 cases showed peripheral cystic changes in MRI images.38 cases showed heteroge-neous enhancement,9 cases showed ring-like or band-like enhancement.13 cases showed cerebrospinal fluid dissemination.The mean minimum apparent diffusion coefficient(ADC)value was(0.61±0.11)× 10-3mm2/s.Spinal AT/RT manifested as solitary or mul-tiple intramedullary and/or extradural lesions on MRI,which showed unclear boundary from the spinal cord.Hemorrhage within or at the edge of the lesion was seen in 2 cases,involvement of nerve roots and adjacent muscle tissues in 3 cases,and cerebrospinal fluid dissemination of the intracranial and spinal cord at varying degrees in 5 cases.Conclusion The imaging findings of pediatric AT/RT in the central nervous system are diverse,combining imaging characteristics with age of onset facilitates the accurate diagnosis.
