MRI and clinical features analysis of squamous carcinoma transformation-mature teratoma of the ovary
10.3969/j.issn.1002-1671.2025.11.016
- VernacularTitle:卵巢成熟畸胎瘤鳞癌转化的MRI及临床特征分析
- Author:
Shiping YANG
1
;
Chao ZHENG
;
Ziwei XU
;
Yaoping SHI
;
Jingyi LI
Author Information
1. 中南大学湘雅医学院附属常德医院(常德市第一人民医院)医学影像科,湖南 常德 415003
- Publication Type:Journal Article
- Keywords:
mature teratoma;
squamous cell carcinoma;
ovarian;
magnetic resonance imaging;
diffusion weighted imaging;
appar-ent diffusion coefficient
- From:
Journal of Practical Radiology
2025;41(11):1835-1837,1856
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the MRI and clinical features of squamous carcinoma transformation-mature teratoma(SCT-MT)of the ovary.Methods The pre-operative data from 7 patients with SCT-MT confirmed by surgery and pathology were collected.The MRI features(such as location,morphology,size,signal,boundaries,and the presence of a mural nodule,with or without fat or calcifi-cation,limited diffusion,transmural growth,and angle to the cyst wall)and clinical features(including age,clinical manifestations,serologi-cal markers,pelvic effusion,peripheral tissue infiltration,and lymph node metastasis)were retrospectively analyzed.Results Among the seven SCT-MT,all originated unilaterally,and were cystic-solid masses with a predominantly cystic component of round or round-like appearance.Six cases had well-defined boundaries,and six exhibited fat-fluid levels.The tumor sizes ranged from 9 cm to 17 cm.Seven cases showed mural nodules,without calcification and fat,with limited diffusion,and the mean apparent diffusion coefficient(ADC)value was(0.96±0.11)× 10-3 mm2/s.Six cases showed transmural growth,and the angle between the nodule and the cyst wall was obtuse in 5 cases,and the mural nodules were significantly enhanced.The seven SCT-MT patients ranged in age from 53 to 75 years old.Four patients had clinical manifestations of pain related to pelvic distension.Conclusion SCT-MT MRI typically presents as a unilateral large solid mass in the pelvic cavity,with a predominantly cystic component.The mural nodules within it lack calcification or fat,show limited diffusion,and may breech the wall and infiltrate adjacent structures,with significant enhancement.Furthermore,SCT-MT may be associated with older age and elevated serological markers.
