Effects of Shenling Baizhu Oral Liquid on intestinal barrier and intestinal flora of broilers
10.16303/j.cnki.1005-4545.2025.05.21
- VernacularTitle:参苓白术口服液对肉鸡肠道屏障及肠道菌群的影响
- Author:
Chanchan CUI
1
;
Shijia ZHANG
;
Qiongyi ZHANG
;
Xiao WANG
;
Xicui DU
;
Wanyu SHI
;
Yongzhan BAO
;
Fuxing CHEN
Author Information
1. 河北农业大学中兽医学院,河北保定 071000
- Publication Type:Journal Article
- Keywords:
Shenling Baizhu Oral Liquid;
intestinal mucosal barrier;
intestinal flora;
broiler chickens
- From:
Chinese Journal of Veterinary Science
2025;45(5):1045-1052
- CountryChina
- Language:Chinese
-
Abstract:
A total of 300 1-day-old broilers were randomly divided into 5 groups with 5 replicates per group and 12 broilers per replicate.The control group was given free drinking water(CG),the astragalus polysaccharide control group(HPS)received 0.8 mL/L of astragalus polysaccharide o-ral liquid in drinking water,and the experimental groups(SBL,SBM,SBH)received 1.5,3.0,4.5 mL/,of Shenling Baizhu Oral Liquid in drinking water.The results showed as follows:com-pared to the CG group,SIgA content in HPS group,group SBM and group SBH was significantly increased(P＜0.05),IL-6 and IL-1β contents were significantly decreased(P＜0.05),Occludin,Mucin-2 and Bcl-2 contents were significantly increased(P＜0.05).The results of 16S rRNA test showed that the specific OUT number in groups HPS and SBM was significantly higher than that in group CG(P＜0.05),α diversity analysis showed that compared with group CG,Chao1 index and Simpson index of group HPS,group SBM and group SBH were significantly increased,and βdiversity analysis showed that there were significant differences in species composition between test group and blank control group(P＜0.05).The relative abundance analysis at the phylum level showed that the relative abundance of Firmicutes and Bacteroides in groups SBM and SBH was significantly higher than that in group CG(P＜0.05).The above results showed that Shenling Baizhu Oral Liquid could improve the intestinal health and enhance the resistance of broilers.
