Current status of clinical application of Shengmaisan in the treatment of chronic heart failure
10.13699/j.cnki.1001-6821.2024.22.022
- VernacularTitle:生脉散治疗慢性心力衰竭的临床应用现状
- Author:
Xin-ran GENG
1
;
Shuo YANG
Author Information
1. 辽宁中医药大学第四临床学院,辽宁沈阳 110847
- Publication Type:Journal Article
- Keywords:
Shengmaisan;
chronic heart failure;
clinical application;
mechanism of action
- From:
The Chinese Journal of Clinical Pharmacology
2024;40(22):3328-3332
- CountryChina
- Language:Chinese
-
Abstract:
Chronic heart failure(CHF)has high morbidity and mortality.The application of Shengmaisan in traditional Chinese medical science has unique advantage in the treatment of chronic heart failure.Shengmaisan can improve the clinical symptoms and quality of life of patients with heart failure.It mainly plays its role through inhibition of neuroendocrine system,inhibition of immune inflammation response,inhibition of myocardial fibrosis,inhibition of cardiomyocyte apoptosis,anti-oxidative stress response,reduced Ca2+leakage and increase myocardial contractility.This article discusses the treatment of chronic heart failure with Shengmaisan in recent years,in order to better clinical application.
