Research status of population pharmacokinetics of tacrolimus in patients with non-transplant diseases
- VernacularTitle:他克莫司在非移植患者中的群体药代动力学研究现状
- Author:
Yuan-yuan ZHENG
1
;
Yu-jie YUAN
1
;
Shu-meng FU
1
;
Xiao-ru HUANG
1
;
Wei ZHAO
1
;
Guo-xiang HAO
1
Author Information
- Publication Type:Journal Article
- Keywords: tacrolimus; population pharmacokinetics; non-transplant diseases; personalized medicine
- From: The Chinese Journal of Clinical Pharmacology 2024;40(22):3358-3362
- CountryChina
- Language:Chinese
- Abstract: Tacrolimus is the first immunosuppressive choice for organ transplantation.It is also used in the immunotherapy of many non-transplant diseases.Because of its large individual variabilities and narrow treatment window,the individualized administration for tacrolimus taking advantage of population pharmacokinetics is necessary.This article aims to summarize population pharmacokinetics studies of tacrolimus in patients with non-transplant diseases and its influencing factors,and to provide a reference for rational use of tacrolimus.
