Development and validation of a predictive model for delayed resuscitation of general anaesthesia in patients with pancreatic cancer surgery
10.3969/j.issn.1671-8283.2025.04.002
- VernacularTitle:胰腺癌患者全身麻醉苏醒延迟风险预测模型的构建与验证
- Author:
Min ZHANG
1
;
Qi ZOU
1
;
Xingjun WANG
1
;
Shuangyuan LIU
1
;
Jingwu GE
1
Author Information
1. 南京医科大学第一附属医院麻醉与围术期医学科,江苏 南京,210029
- Publication Type:Journal Article
- Keywords:
delayed resuscitation;
pancreatic cancer;
general anaesthesia;
prediction model;
cross-sectional study
- From:
Modern Clinical Nursing
2025;24(4):8-14
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influencing factors for delayed resuscitation from anaesthesia in patients undergoing pancreatic cancer surgery and to develop a prediction model and evaluate its predictive performance.Methods This study included 300 patients who had surgery under general anaesthesia for pancreatic cancer at a Tier-IIIA hospital in Jiangsu Province between September 2023 and February 2024.The patients who had the surgery between September and December 2023(n=208)were assigned to the modelling group,and those between January to February 2024(n=92)to the validation group.Baseline perioperative data were recorded.Binary logistic regression was used to identify risk factors for delayed resuscitation,and a risk prediction model was finally developed and validated.Results Over 60 years of age,bispectral index(BIS)monitoring,combined with regional block anaesthesia,and rescue analgesia were identified as the risk factors for delayed resuscitation(all P<0.05).The Hosmer-Lemeshow test confirmed a good model fit(P>0.05).The C-index value was 0.807 for the modelling group and 0.841 for the validation group.The area under the curve(AUC)of receiver operating characteristic(ROC)was 0.807(95%CI 0.738～0.876)for the modelling group and 0.841(95%CI 0.742～0.940)for the validation group,with both calibration curves close to the ideal curve.Conclusion The developed prediction model for delayed resuscitation exhibits a good predictive performance and it can serve as a reference for clinical staff.
