Research progress in vaccine development for severe fever with thrombocytopenia syndrome
10.3969/j.issn.1002-2694.2025.00.044
- VernacularTitle:发热伴血小板减少综合征疫苗研究进展
- Author:
Dong-shen JIANG
1
;
Bo-bo WANG
;
Fang-lin ZHANG
;
Wei YE
Author Information
1. 延安大学医学院,延安市动物及人兽共患寄生虫病重点实验室,延安 716000;空军军医大学基础医学院微生物与病原生物学教研室,西安 710032
- Publication Type:Journal Article
- Keywords:
Dabie Bandavirus(DBV);
severe fever with thrombocytopenia syndrome virus(SFTSV);
severe fever with thrombocytopenia syndrome(SFTS);
subunit vaccines;
recombinant vector vaccines;
DNA vaccine;
mRNA vaccine
- From:
Chinese Journal of Zoonoses
2025;41(3):322-330,338
- CountryChina
- Language:Chinese
-
Abstract:
Severe fever with thrombocytopenia syndrome(SFTS)is an acute infectious disease caused by the Dabie Banda-virus(DBV),with a high mortality rate.The annually reported number of cases is steadily increasing.DBV is transmitted pri-marily by tick bites,and its epidemic range is gradually expanding with the spread of its vector,thus posing a serious threat to human health.No licensed preventive vaccine is currently available.The World Health Organization has listed SFTS as an infec-tious disease requiring further investigation of vaccines and treatments with high priority.This article reviews current research progress in SFTS vaccines,to provide a reference for the development of DBV vaccines.