Foreign body granuloma at the injection site caused by progesterone injection
10.3760/cma.j.cn114015-20220525-00463
- VernacularTitle:黄体酮注射液致注射部位异物肉芽肿
- Author:
Jimei GAN
1
;
Xiaojun HAN
;
Yao HUANG
;
Guoqiang XU
;
Qiao YANG
Author Information
1. 成都市温江区人民医院药学部，成都 611130
- Publication Type:Journal Article
- Keywords:
Progesterone;
Granuloma, foreign-body
- From:
Adverse Drug Reactions Journal
2023;25(6):376-378
- CountryChina
- Language:Chinese
-
Abstract:
A 31-year-old female patient accidentally found a bean-sized lump under the right buttock, causing slight pain when pressing. Ultrasound examination revealed multiple cystic nodules of varying sizes in the subcutaneous fat layer of the right buttock. The patient underwent right buttock mass resection and was diagnosed as foreign body granuloma according to the postoperative pathology and medical history. Five years ago, the patient received bilateral intramuscular injection of progesterone (10-15 mg once daily) into the buttocks for 3 months due to threatened miscarriage. Afterwards, no other medication was injected into the buttocks. Therefore, it was considered that the foreign body granuloma in her buttock was related to the injection of progesterone. Two months later, the patient underwent extended resection of soft tissue tumor under the gluteus maximus muscle of the left buttock, and the postoperative pathological results were the same as that of the first time.
