Elevation of blood pressure in a patient with progressive muscular dystrophy due to levocarnitine
10.3760/cma.j.cn114015-20220420-00339
- VernacularTitle:左卡尼汀致进行性肌营养不良患者血压升高
- Author:
Fei WANG
1
;
Gang LIU
;
Zhuolin YIN
;
Yan ZHANG
Author Information
1. 首都医科大学宣武医院神经内科，北京 100053
- Publication Type:Journal Article
- Keywords:
Muscular dystrophies;
Hypertension;
Levocarnitine
- From:
Adverse Drug Reactions Journal
2023;25(6):374-375
- CountryChina
- Language:Chinese
-
Abstract:
A 23-year-old male patient with progressive muscular dystrophy received intravenous injection of levocarnitine 1 g twice daily. Before the medication, the patient′s blood pressure was 120/70 mmHg. After 15 minutes of the first administration, the patient′s blood pressure increased to 156/90 mmHg, accompanied by chest tightness and headache; 4 hours later, it increased to 196/138 mmHg; 12 hours later, it decreased to 158/106 mmHg. After the second intravenous injection of levocarnitine on the same day, the elevation of blood pressure recurred. The elevation of blood pressure was considered to be caused by levocarnitine. The drug was discontinued the next day, and the patient′s blood pressure gradually returned to the reference range. Thereafter, the patient did not experience any symptoms such as elevated blood pressure, chest tightness, or headache.
