Comparative Experimental Study of Nd∶YAG Laser Ablation of Fresh Isolated Pig Liver
10.13241/j.cnki.pmb.2025.10.002
- VernacularTitle:Nd∶YAG激光消融新鲜离体猪肝的对比实验研究
- Author:
Ruo-yu LIU
1
;
Mu YUAN
1
;
Hao LI
1
;
Zi-yi ZHU
1
;
Yu-lin TAN
1
Author Information
1. 蚌埠医科大学第一附属医院介入科 安徽 蚌埠 233004
- Publication Type:Journal Article
- Keywords:
Nd∶YAG laser;
Ablation;
Fresh isolated pig liver;
Comparative experimental
- From:
Progress in Modern Biomedicine
2025;25(10):1613-1619,1657
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the characteristics and temperature changes of single and double fiber Nd∶YAG laser in fresh isolated pig liver,and to provide reference for clinical ablation treatment.Methods:Single-needle single-point and double-needle double-point ablations were perf ormed on fresh isolated pig livers using a 5 W power laser,and the morphology,range,and surrounding temperature changes of the ablation lesions caused by the two in vitro liver tissues were observed.Results:The ablation lesions were divided into carbonized area,necrotic area and deformed area from inside to outside.The carbonized area in the center of the ablation lesion in the double-fiber group was larger and the cell necrosis was more thorough.The aspect ratio(LD/TD)of the laser ablation lesion in the single-fiber group was larger than that in the double fiber group(P＜0.001).The transverse diameter(TD)and volume(V)of the ablation lesion in the double-fiber group were larger than those in the single-fiber group(P＜0.001).There was no significant difference in the longitudinal diameter(LD)of the ablation lesion between the double-fiber group and the single-fiber group(P＞0.05).There was no significant difference in the temperature of 20 s,40 s and 60 s at 5 mm and 10 mm beside the ablation center between the two groups(all P＞0.05).Conclusion:Under the condition of 5 W,the temperature changes around the single and double fiber ablation are similar.The single fiber is suitable for small tumor ablation,and the double fiber ablation range is larger,which can be used for one-time full coverage ablation of larger cancer nodules.
