Research status of Chinese medicine in the prevention and treatment of oligozoospermia
10.13699/j.cnki.1001-6821.2024.21.026
- VernacularTitle:中医药防治少弱精子症的研究现状
- Author:
Xiao-wei JI
1
;
Jia-shu YANG
;
Rui YAN
;
Li-ming LIU
;
Xi-ping XING
Author Information
1. 甘肃中医药大学中西医结合学院,甘肃兰州 730000
- Publication Type:Journal Article
- Keywords:
Chinese medicine;
oligozoospermia;
research status
- From:
The Chinese Journal of Clinical Pharmacology
2024;40(21):3196-3200
- CountryChina
- Language:Chinese
-
Abstract:
Objective Kelch-like epichlorohydrin-associated protein 1/transcription factor NF-E2-associated factor 2/hemoglobin oxygenase 1(Keap1/Nrf2/HO-1),phosphatidylinositol-3 kinase/protein kinase B/rapamycin protein(PI3K/Akt/mTOR),stem cell growth factor/tyrosinase receptor(SCF/c-kit),liver kinase B1/adenylate-activated protein kinase(LKB1/AMPK)and other signaling pathways have irreplaceable roles in the development of oligospermia(OAS),and the study of targeting their related signals is a hotspot for the prevention and treatment of OAS.Therefore,taking many signaling pathways as breakthroughs.The review systematically summarized the mechanism of action of Chinese medicine extracts,proprietary Chinese medicines,Chinese medicine prescriptions and external Chinese medicine treatments such as acupuncture and moxibustion that intervene in the relevant signaling pathways for the treatment of OAS,with a view to providing theoretical basis and guidance for clinical practice.
