Contrast-induced encephalopathy following angiography with iodixanol
10.3760/cma.j.cn114015-20201102-01107
- VernacularTitle:碘克沙醇致对比剂脑病
- Author:
Lili SHEN
1
;
Xinke ZHANG
;
Lujie FAN
;
Xiaohua LI
;
Guoying ZHAO
Author Information
1. 河北省涉县医院药剂科，涉县 056400
- Publication Type:Journal Article
- Keywords:
Contrast media;
Iodixanol;
Encephalopathy
- From:
Adverse Drug Reactions Journal
2021;23(5):266-268
- CountryChina
- Language:Chinese
-
Abstract:
A 71-year-old male patient with severe stenosis of the right common carotid artery and internal carotid artery underwent aortography+cerebral arteriography+right internal carotid artery stenting under local anesthesia with contrast medium iodixanol injection. Head CT before operation showed no obvious abnormality. Ten hours after the operation, the patient developed neurological symptoms such as fever, drowsiness, choking in drinking water, incomplete motor aphasia, decrease of muscle strength and tension of left limb, convulsions, etc. Brain magnetic resonance imaging (MRI) showed increased signal intensity in the right cerebral sulcus and sulcus shallower. Contrast-induced encephalopathy caused by iodixanol was considered. After 3 days of symptomatic treatments with rehydration, glucocorticoid, and mannitol, the patient′s symptoms were improved. Brain MRI showed that the hyperintensity of right cerebral cortex decreased and the sulcus gradually returned to normal.
