Somnambulism induced by montelukast sodium chewable tablets in a pediatric patient
10.3760/cma.j.cn114015-20200412-00401
- VernacularTitle:孟鲁司特钠咀嚼片致儿童梦游
- Author:
Miaomiao LIU
1
;
Shuchen SUN
;
Fan WANG
Author Information
1. 北京中医药大学研究生院中西医结合临床专业，北京 100029
- Publication Type:Journal Article
- Keywords:
Somnambulism;
Drug-related side effects and adverse reactions;
Montelukast sodium;
Sleepwalking
- From:
Adverse Drug Reactions Journal
2021;23(3):148-149
- CountryChina
- Language:Chinese
-
Abstract:
A 6-year-old girl received sinupret oral drops and mometasone furoate aqueous nasal spray for allergic rhinitis for more than 1 month, but her symptoms were not improved. Additional use of oral montelukast sodium chewable tablets 4 mg every night was given due to adenoid hypertrophy. After 7 days of montelukast sodium administration, the girl developed somnambulism once per week, which manifested as sitting up suddenly in the dream and lying down to sleep after 1 minute. Two months later, all drugs were stopped because the nasal symptoms were relieved and no sleepwalking occurred 1 week after drug withdrawal. More than a year later, the above 3 drugs were given by her parents due to the recurrence of rhinitis and the girl developed somnambulism again with worse symptoms 5 days later. After 2 weeks of continued medication, somnambulism continued to worsen. Montelukast sodium was stopped, symptoms of somnambulism were relieved 2 days later and disappeared 1 month later. Considering that somnambulism in the girl was an adverse reaction to montelukast sodium, it was replaced by oral loratadine 5 mg every night. At 3 months of telephone follow-up, the somnambulism did not occur in the girl.
