Application of autofluorescence examination technology in the early warning of potential malignant disea-ses of the oral cavity
10.3969/j.issn.1001-3733.2025.03.015
- VernacularTitle:自体荧光检查技术在口腔潜在恶性疾病早期预警中的应用研究
- Author:
Wanli ZHU
1
;
Zhenlai ZHU
;
Tiantian WU
;
Huan ZHANG
;
Yixin WANG
;
Xi LIU
;
Qing LIU
;
Rui LIU
Author Information
1. 710032 西安,口颌系统重建与再生全国重点实验室,国家口腔疾病临床医学研究中心,陕西省口腔疾病临床医学研究中心,空军军医大学口腔医院口腔黏膜病科
- Publication Type:Journal Article
- Keywords:
VELscope;
Autofluorescence;
Suspected dysplasia;
Precancerous lesions;
Oral cancer
- From:
Journal of Practical Stomatology
2025;41(3):398-401
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To verify the efficacy of VELscope autofluorescence examination technology in the early warning of potential oral malignant diseases.Methods:80 patients with suspected dysplasia were included and underwent oral examination,visually en-hanced lesion scope(VELscope)autofluorescence examination and histopathology examination respectively,the fluorescence imaging results were compared with the histopathological results.Results:Pathological reports showed 64 cases with mild or no dysplasia,9 cases with moderate or severe dysplasia,1 case with moderate dysplasia without malignant transformation and 6 cases with cancer.The results of VELscope showed that there were 73 positive cases and negative 7 cases of fluorescence deletion.The sensitivity and specificity of VELscope were 93.75％and 9.37％respectively,and the sensitivity could reach 100％in the cancerous tissue.Con-clusion:As a non-invasive examination method,VELscope is highly sensitive but lowly specific.
