Expert consensus on holistic integrative management of oropharyngeal squamous cell carcinoma
- VernacularTitle:口咽鳞状细胞癌整合诊治专家共识
- Author:
Moyi SUN
1
;
Zongxuan HE
;
Qianwei NI
;
Xiaoying LI
;
Lin KONG
;
Qing XI
;
Wei GUO
;
Zhangui TANG
;
Guoxin REN
;
Zhijun SUN
;
Jian MENG
;
Jie ZHANG
;
Jichen LI
;
Yue HE
;
Chunjie LI
;
Lizheng QIN
;
Kai YANG
;
Bing HAN
;
Yan SUN
;
Haijun LU
;
Xiaohong ZHAN
;
Dapeng HAO
;
Kai SONG
;
Haoyue XU
;
Lingxue BU
;
Jieying LI
;
Man HU
;
Mingjin XU
;
Yun LI
;
Wei SHANG
Author Information
- Publication Type:Journal Article
- Keywords: Oropharyngeal squamous cell carcinoma; Human papillomavirus; Multidisciplinary team; Holistic integrative management
- From: Journal of Practical Stomatology 2025;41(3):293-304
- CountryChina
- Language:Chinese
- Abstract: Oropharyngeal squamous cell carcinoma(OPSCC)is a malignant tumor originating from the squamous epithelium of the oro-pharyngeal mucosa,accounting for more than 90％of oropharyngeal malignancies.In recent years,human papillomavirus(HPV)infec-tion has become one of the primary etiological factors of oropharyngeal squamous carcinoma.The incidence of HPV-associated oropharyn-geal squamous carcinoma has been rising annually,with a noticeable trend toward younger populations,posing a significant threat to hu-man health.Due to the distinct biological behavior and clinical characteristics of HPV-associated oropharyngeal squamous carcinoma com-pared to its non-HPV-related counterpart,the diagnostic and treatment strategies for oropharyngeal squamous carcinoma have undergone substantial changes.Prevention and screening for oropharyngeal squamous carcinoma are of critical importance.The diagnostic and treat-ment process involves multi-disciplinary collaboration,including oral and maxillofacial surgery,otolaryngology,head and neck surgery,oncology,radiology and pathology.Based on evidence from clinical practice,a comprehensive,integrated diagnostic and therapeutic ap-proach has been established,centered around the concept of"prevention,screening,diagnosis,treatment,and rehabilitation",covering the entire patient lifecycle and providing a valuable reference for clinical practice.
