Diabetes mellitus and hemocytopenia induced by overdose of Tetrastigma hemsleyanum
10.3760/cma.j.cn114015-20200820-00896
- VernacularTitle:超量服用三叶青致糖尿病和血细胞减少
- Author:
Yanqing LIU
1
;
Qingping LIU
1
;
Xia DING
1
;
Pingfu ZHANG
1
;
Yanhong MA
1
Author Information
1. 浙江省安吉县中医医院肿瘤科，安吉 313300
- Publication Type:Journal Article
- Keywords:
Plants, medicinal;
Diabetes mellitus;
Tetrastigma hemsleyanum
- From:
Adverse Drug Reactions Journal
2021;23(3):154-155
- CountryChina
- Language:Chinese
-
Abstract:
A 76-year-old female patient took soaking water of Tetrastigma hemsleyanum 15 g daily by herself after lung cancer resection and chemotherapy. After 3 months of medication, the patient developed fatigue and dry mouth. After 4 months of medication, decrease of white blood cells and hemoglobin and increase of fasting blood glucose and glycosylated hemoglobin appeared and were gradually aggravated. After 6 months of medication, the white blood cell count was 2.8×10 9/L, hemoglobin was 88 g/L, red blood cell count was 3.05×10 12/L, fasting blood glucose was 10.01 mmol/L, and glycosylated hemoglobin was 6.93%. Diabetes mellitus, leukopenia, and anemia were diagnosed, which were considered to be related to Tetrastigma hemsleyanum. The patient was asked to stop drinking the soaking water of Tetrastigma hemsleyanum and the traditional Chinese medicine decoction was given. Two months later, the patient′s blood cells returned to normal, fasting blood glucose was 6.08 mmol/L, and glycosylated hemoglobin was 6.10%. The prescribed daily dose of Tetrastigma hemsleyanum in Chinese Medicine Record is 3-9 g. Diabetes mellitus and hemocytopenia in the patient might be related to overdose and long-time use of the drug.
