Research progress on the mechanisms and detection methods of retinal photo-damage
10.13389/j.cnki.rao.2025.0086
- VernacularTitle:视网膜光损伤的机制及检测方法的研究现状
- Author:
Dongrui XIA
1
;
Mengtian KANG
1
Author Information
1. 100730 北京市,首都医科大学附属北京同仁医院,同仁眼科中心,北京市眼科研究所
- Publication Type:Journal Article
- Keywords:
retinal photodamage;
phototoxicity;
retinopathy;
apoptosis;
photoreceptor cell
- From:
Recent Advances in Ophthalmology
2025;45(6):490-494
- CountryChina
- Language:Chinese
-
Abstract:
The mechanisms underlying retinal photodamage are multifaceted,encompassing oxidative stress,calcium overload,rhodopsin-mediated injury,lipofuscin accumulation,glial cell activation,inflammatory response,DNA fragmen-tation,etc.Currently,multiple detection methods are available to evaluate retinal photodamage,encompassing electro-physiological functional assessment,morphological analysis,apoptotic cell detection,immunofluorescence labeling,and so on.This review focuses on the research progress on both the mechanisms and detection methods of retinal photodamage.
