Pathogenesis and treatment of breast cancer from the perspective of"blood cold accumulation at the uterine ostium"
10.3969/j.issn.1006-2157.2025.05.017
- VernacularTitle:从"血寒积结胞门"探析乳腺癌的病机与治疗
- Author:
Yiming ZHANG
1
;
Fen LIU
;
Shan GE
;
Zijian WANG
;
Jing ZHAO
;
Luning LI
;
Shulong JIANG
Author Information
1. 山东中医药大学第一临床医学院 济南 250014
- Publication Type:Journal Article
- Keywords:
breast cancer;
Synopsis of Golden Chamber;
uterus;
Wenjing Decoction;
Xiaoyao Powder
- From:
Journal of Beijing University of Traditional Chinese Medicine
2025;48(5):711-716
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer remains a substantial threat to women's health and is one of the most prevalent malignant tumors in women.Because breast cancer onset is closely associated with female physiological characteristics,this article proposes that breast cancer be classified as a"women's miscellaneous diseases"and that its treatment be explored from this perspective.Drawing from Chapter 8 on Golden Chamber of Prescriptions for Miscellaneous Diseases in Women of Synopsis of Golden Chamber,the initial pathogenesis of breast cancer is associated with"emotional stress,improper lifestyle,deficiency,cold,and stagnation."The fundamental mechanism behind its formation is"blood cold accumulation and hardened masses."Specifically,emotional imbalance and improper lifestyle habits contribute to the combined invasion of the uterus by"deficiency,""accumulated cold,"and"stagnant qi."Over time,"cold-blood stasis accumulates at the uterine ostium,"and the cold and the stasis ascends from the uterus along the thoroughfare and conception vessels,obstructing the breast collaterals.This combination of yang qi stagnation and yin cold congealment,ultimately leads to the development of breast cancer.The treatment principle should focus on"activating yang and dispersing cold."A therapeutic approach centered on Wenjing Decoction combined with Xiaoyao Powder can be adapted based on the stage and type of breast cancer while also considering the dynamic interplay between pathogenic factors and healthy qi,along with shifts in deficiency and excess patterns of disease.By adhering to the principles of consistency and flexibility and integrating disease and syndrome differentiation,the goal is to develop precise and personalized treatment strategies to improve clinical outcomes.
