Postpartum hemorrhage and coagulation disorder following pregnancy in a patient with neuromyelitis optica spectrum disorder:one case report
10.3969/j.issn.1672-8467.2025.03.020
- VernacularTitle:视神经脊髓炎谱系障碍妊娠后并发产后出血及凝血功能障碍1例报告
- Author:
Yi SUN
1
;
Qian-qian ZHANG
1
;
Lin LIN
1
Author Information
1. 复旦大学附属妇产科医院产科 上海 200011
- Publication Type:Journal Article
- Keywords:
neuromyelitis optica spectrum disease(NMOSD);
coagulation dysfunction;
postpartum hemorrhage;
pregnancy
- From:
Fudan University Journal of Medical Sciences
2025;52(3):466-469
- CountryChina
- Language:Chinese
-
Abstract:
Neuromyelitis optica spectrum disorder(NMOSD)is an autoimmune neurological condition characterized by relapsing optic neuritis and longitudinally extensive transverse myelitis.Patients with NMOSD are prone to adverse pregnancy outcomes,intrapartum complications,high relapse rates,and significant disability following pregnancy.This paper analyzes a case of NMOSD experienced exacerbation of symptoms during pregnancy and childbirth,postpartum hemorrhage accompanied by coagulopathy,and ultimately successful resuscitation.We propose that active administration of corticosteroids and intravenous immunoglobulin during labor is an effective and feasible strategy for controlling the disease.Rapid replenishment of coagulation factors and timely correction of coagulation function are essential to prevent adverse outcomes.The paper summarizes the prenatal care and childbirth-related risks for such patients,and provides insights for the optimization of management protocols.
