Sodium phosphates oral solution-induced acute attack of gout: report of 3 cases
10.3760/cma.j.cn114015-20181221-01272
- VernacularTitle:磷酸钠盐口服溶液诱导痛风急性发作3例
- Author:
Weina GAO
1
;
Yihong XIE
Author Information
1. 西藏自治区人民政府驻成都办事处医院消化内科 610041
- Publication Type:Journal Article
- Keywords:
Phosphates;
Gout;
Symptom flare up;
Uric acid;
Crystallization
- From:
Adverse Drug Reactions Journal
2020;22(4):264-265
- CountryChina
- Language:Chinese
-
Abstract:
Three Tibetan male patients (patient 1, 64-year-old; patient 2, 51-year-old; patient 3, 39-year-old) with previous history of gout received sodium phosphates oral solution 90 ml in intestinal preparation for endoscopic examination or treatment. The patients all developed typical gout attack on day 2 after their medications, but their blood uric acid levels were lower than those before taking the medicine (patient 1, from 526 μmol/L to 417 μmol/L; patient 2, from 566 μmol/L to 374 μmol/L; patient 3, from 465 μmol/L to 379 μmol/L), respectively. The acute attack of gout in the 3 patients was considered to be related with sodium phosphates oral solution, but whether it was related with phosphate crystallization was not determined.
