Temporary urinary incontinence due to dexamethasone sodium phosphate injection
10.3760/cma.j.cn114015-20190508-00411
- VernacularTitle:地塞米松磷酸钠注射液致暂时性尿失禁
- Author:
Kun JIANG
1
;
Linjing SONG
;
Lina YOU
Author Information
1. 云南昆钢医院药学部，昆明 650302
- Publication Type:Journal Article
- Keywords:
Dexamethasone;
Urinary incontinence;
Drug-related side effects and adverse reactions
- From:
Adverse Drug Reactions Journal
2020;22(9):529-530
- CountryChina
- Language:Chinese
-
Abstract:
A 64-year-old female patient with endometrial cancer received an IV infusion of dexamethasone sodium phosphate injection 10 mg dissolved in 5% glucose injection 100 ml before chemotherapy to prevent allergic reaction induced by paclitaxel. The infusion was finished within about 30 minutes and the patient had no discomfort during the infusion. About 2 hours later, the patient developed urinary incontinence without urgent and painful urination, which gradually disappeared. Two hours after the second intravenous infusion of dexamethasone sodium phosphate injection, urinary incontinence recurred. After the intravenous infusion of dexamethasone sodium phosphate injection was replaced by oral dexamethasone tablets, the symptoms of urinary incontinence were alleviated. It was considered that the temporary urinary incontinence was probably related to dexamethasone sodium phosphate.
