Clinical case analysis of novel coronavirus pneumonia complicated with pulmonary hypertension
10.3760/cma.j.cn114015-20200509-00506
- VernacularTitle:新型冠状病毒肺炎并发肺动脉高压临床病例分析
- Author:
Lianshuang WANG
1
;
Li BAI
;
Jing YU
;
Liping WANG
;
Xuemei WANG
;
Pan XIANG
;
Xuesong GAO
;
Yao ZHANG
Author Information
1. 首都医科大学附属北京地坛医院超声科 100015
- Publication Type:Journal Article
- Keywords:
Coronavirus infections;
Echocardiography;
Hypertension, pulmonary
- From:
Adverse Drug Reactions Journal
2020;22(6):355-359
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To report the clinical features of pulmonary hypertension diagnosed by echocardiography in 5 patients with novel coronavirus pneumonia (COVID-19) in order to understand the special clinical manifestations of COVID-19 and explore the possible mechanism.Methods:The echocardiographic data and clinical characteristics of COVID-19 patients complicated with pulmonary hypertension diagnosed by echocardiography in Beijing Ditan Hospital, Capital Medical University were analyzed descriptively from February 5 to March 31, 2020.Results:A total of 15 patients with severe and critical COVID-19 patients underwent echocardiography. Of them, 7 patients were diagnosed with pulmonary hypertension, 5 of which were confirmed as complications of COVID-19. Among the 5 patients, 4 were female and 1 was male, aged 62-78 years; 4 were with hypertension, 3 were with diabetes, and 1 was with coronary atherosclerotic heart disease. All 5 critically ill patients with COVID-19 were given ventilator-assisted breathing, 2 of which were given extracorporeal membrane oxygenation at the same time. According to echocardiography, the systolic pressure of pulmonary artery in 5 patients was 43-65 mmHg, with an average of 54 mmHg. The severity of pulmonary hypertension was graded as mild in 1 patient and moderate in 4 patients. During the follow-up, pulmonary artery systolic pressure gradually decreased to normal in 4 patients, and then ventilator and ECMO were withdrawn; 1 patient died due to respiratory failure and persistent pulmonary hypertension.Conclusions:Patients with COVID-19 may be complicated by pulmonary hypertension, which is often found in the critical patients. Echocardiography is an important imagingdiagnostic method for pulmonary hypertension in patients with COVID-19.
