CT features of pleuropulmonary blastoma in children
10.3969/j.issn.1002-1671.2025.05.026
- VernacularTitle:儿童胸膜肺母细胞瘤CT特征
- Author:
Hua CHEN
1
;
Yuewen HAO
1
;
Xin HOU
1
Author Information
1. 西安市儿童医院影像科,陕西 西安 710003
- Publication Type:Journal Article
- Keywords:
children;
pleuropulmonary blastoma;
computed tomography;
pathological type;
Dehner typing
- From:
Journal of Practical Radiology
2025;41(5):837-839,869
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the CT features of pediatric pleuropulmonary blastoma(PPB)and its clinical application value.Methods The CT features of 9 patients with PPB confirmed by postoperative pathology were analyzed retrospectively and compared with the postoperative pathological types.Results There was 1 case with type Ⅰ PPB,whose CT manifestations were multilocular septated cystic space-occupying lesions,with mild enhancement of the cyst wall and septum after enhancement,and was misdiagnosed as type Ⅳ congenital pulmonary airway malformation(CPAM)before surgery.There were 2 cases with type Ⅱ PPB,whose CT manifestations were well-defined cystic and solid space-occupying lesions,closely related to the pleura,with uneven mild to moderate progressive enhancement of the solid components,and multiple thickened and tortuous blood vessels were visible in both lesions.The preoperative imaging diagnosis and pathological type prediction of type Ⅱ PPB,lesions were completely consistent with the post-operative pathological diagnosis and type,with a diagnostic accuracy of 100％.There were 6 cases with type Ⅲ PPB,whose CT man-ifestations were solid soft tissue density space-occupying lesions,with uneven enhancement of the solid part after enhancement,and multiple thickened and tortuous blood vessels within the masses.Before surgery,2 cases(33.3％)with type Ⅲ PPB were misdiag-nosed as Askin tumors of the chest wall,and the diagnostic accuracy was 66.7％.Conclusion PPB is a rare tumor in the chest of children,with high malignancy.Type Ⅰ PPB is difficult to be differentiated from benign cystic lesions of the chest before surgery.For suspected type Ⅰ PPB pulmonary cystic lesions,the postoperative pathological sampling should be extensive to search for whether there are primitive mesenchymal cells for a clear diagnosis.The CT features of type Ⅱ and Ⅲ PPB are cystic-solid and solid masses in the chest,with clear boundaries,pseudocapsules,and nodular enhancement.Generally,the consistency rate between preoperative imaging diagnosis and pathological type prediction and postoperative pathological diagnosis and type is relatively high.Combining the CT characteristics of PPB is helpful to improve the accuracy of preoperative diagnosis and pathological type prediction,and can assist clinicians in selecting reasonable treatment plans.
