To construct a nomogram model for severe mycoplasma pneumoniae pneumonia coinfection with other pathogens in children
10.3969/j.issn.1002-1671.2025.05.024
- VernacularTitle:构建儿童重症肺炎支原体肺炎合并其他病原体感染的列线图模型
- Author:
Wenbei XU
1
;
Chenzi WANG
;
Juan LONG
;
Xiaohan LIU
;
Lingjian MENG
;
He ZHANG
;
Xiaonan SUN
;
Haiquan KANG
;
Yiping MAO
;
Yankai MENG
;
Chunfeng HU
;
Kai XU
Author Information
1. 徐州医科大学附属医院医学影像科,江苏 徐州 221002;徐州医科大学医学影像学院,江苏 徐州 221002;江苏省医学影像与数字医学工程研究中心,江苏 徐州 221002
- Publication Type:Journal Article
- Keywords:
mycoplasma pneumoniae;
severe mycoplasma pneumoniae pneumonia;
bronchoalveolar lavage
- From:
Journal of Practical Radiology
2025;41(5):828-832
- CountryChina
- Language:Chinese
-
Abstract:
Objective To construct a clinical-radiological nomo-gram model for severe mycoplasma pneumoniae pneumonia coinfec-tion with other pathogens(Co-SMPP)in children.Methods The clinical and radiological data of children with severe mycoplasma pneumoniae pneumonia(SMPP)who underwent nucleic acid testing or bronchoalveolar lavage(BAL)were analyzed retrospectively.The data analysis were performed by using SPSS 27.0 software.The group comparison between simple SMPP and Co-SMPP children was conducted by using t-tests,Mann-Whitney U tests,or chi-square tests.Nomogram analysis was performed by using R software and rms packages.The predictive performance of the model was evaluated by using the receiver operating characteristic(ROC)curve.Results A total of 194 SMPP children were included in the study,including 136 cases(70.1％)with simple SMPP,58 cases(29.9％)with Co-SMPP.The fibrinogen and albumin levels were lower in Co-SMPP children[(3.53±0.85)g/L,41.00(39.03,43.68)g/L]than in simple SMPP children[(3.79±0.80)g/L,42.80(41.00,44.40)g/L],with P values of 0.047 and 0.036,respec-tively.The probability of bronchial stenosis and grid shadow were higher in Co-SMPP children than in simple SMPP children,and there were significant differences between the two groups(P＜0.001,P=0.010).The odds ratio of bronchial stenosis in predicting Co-SMPP children was 14.085.The clinical-radiological nomogram model had an area under the curve(AUC)of 0.840,with sensi-tivity and specificity of 0.756 and 0.848,respectively.Conclusion The nomogram model based on clinical-radiological features can effectively predict Co-SMPP.
