Liver abscesses caused by Streptococcus:report of 21 cases
10.16718/j.1009-7708.2025.03.006
- VernacularTitle:链球菌肝脓肿21例
- Author:
Qin LONG
1
;
Xiaoyu ZHAO
;
Chang CHEN
;
Min HAO
;
Xiaohua QIN
Author Information
1. 复旦大学附属华山医院抗生素研究所,上海 200040;湖南中医药高等专科学校附属第一医院(湖南省直中医医院)呼吸与危重症医学科
- Publication Type:Journal Article
- Keywords:
Streptococcus;
liver abscess;
treatment
- From:
Chinese Journal of Infection and Chemotherapy
2025;25(3):272-278
- CountryChina
- Language:Chinese
-
Abstract:
Objective To improve the diagnosis and treatment of Streptococcus liver abscesses by analyzing the clinical presentations,antibiotic susceptibility,and treatment strategies of patients.Methods A retrospective analysis was conducted on 21 patients diagnosed with liver abscess caused by Streptococcus from June 2012 to June 2022.The data included demographic information,clinical characteristics,laboratory tests,imaging findings,treatment strategies,and outcomes.Results The 21 patients were 29 to 77 years of age,and 81.0％were male.Clinical manifestations included fever,chills,fatigue,and abdominal pain.Some patients also had headache and altered consciousness,indicating possible concomitant brain abscess.Hematogenous dissemination and biliary tract origin were the most common routes of infection.The predominant pathogen was Streptococcus anginosus group(76.2％).Single pathogen infection was found in 12 cases and mixed infection in 9 cases.All isolates were sensitive to penicillin,cefotaxime,vancomycin,and levofloxacin,but 36.4％(4/11)of the isolates showed resistance to erythromycin and clindamycin.Four patients developed metastatic abscesses,and two experienced septic shock.The main treatment approach was a combination of antibiotics and percutaneous liver puncture drainage,resulting in improvement in 18 patients.Conclusions Liver abscesses caused by Streptococcus are usually non-specific in terms of symptoms.Streptococcus anginosus group is the primary pathogen.Antibiotics combined with percutaneous drainage is an effective treatment approach.It is crucial for clinicians to be aware of potential brain abscesses and the necessity of early intervention.
