Expression level of neutrophil/lymphocyte ratio and monocyte/high density lipoprotein cholesterol ratio in patients with sudden deafness and their correlation with prognosis
10.3969/j.issn.1006-5725.2024.24.011
- VernacularTitle:中性粒细胞/淋巴细胞比率和单核/高密度脂蛋白胆固醇比率在突发性耳聋患者中的表达水平及与预后的相关性
- Author:
Hongmei ZHU
1
;
Yongjiu HUANG
1
;
Jiusheng CHU
1
;
Xiuhong PANG
1
Author Information
1. 南京医科大学附属泰州人民医院耳鼻喉头颈外科(江苏 泰州 225300)
- Publication Type:Journal Article
- Keywords:
neutrophil/lymphocyte ratio;
monocyte/high density lipoprotein cholesterol ratio;
sudden deafness;
prognosis;
correlation analysis
- From:
The Journal of Practical Medicine
2024;40(24):3503-3508
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between neutrophil/lymphocyte ratio(NLR)and mono-cyte/high density lipoprotein cholesterol ratio(MHR)and the onset and prognosis of sudden deafness(SSNHL).Methods 138 patients with sudden deafness who were treated in the hospital from January 2022 to May 2024 were selected as the study group,and 116 normal healthy people were selected as the control group.The changes of NLR and MHR in two groups and different types of SSNHL patients were compared.Logistic regression was used to explore the prognostic factors of patients with SSNHL.Results NLR and MHR in the study group were signifi-cantly higher than those in the control group(P＜0.05).There were statistical differences in the average hearing threshold,total cholesterol(TC),fibrinogen(FIB),platelet count(PLT),cortisol(COR),NLR and MHR in patients with different types of SSNHL(P＜0.05).NLR,MHR and SSNHL were significantly correlated(P＜0.05).The increase of NLR and MHR is a risk factor for poor prognosis in patients with SSNHL.Conclusion NLR and MHR are closely related to the pathogenesis of SSNHL and are important factors leading to poor prognosis of patients with SSNHL.
