Clinical effect of aortic root replacement in adolescent patients with aortic root aneurysm
10.3760/cma.j.cn431274-20250706-00896
- VernacularTitle:青少年主动脉根部瘤患者行主动脉根部替换术的临床效果
- Author:
Chenhan ZHANG
1
;
Xiaoyang ZHANG
1
;
Suwei CHEN
1
;
Zhiyu QIAO
1
;
Haiou HU
1
;
Yipeng GE
1
;
Chengnan LI
1
;
Junming ZHU
1
Author Information
1. 首都医科大学附属北京安贞医院主动脉外科中心，北京 100029
- Publication Type:Journal Article
- Keywords:
Aortic root aneurysm;
Aortic root replacement;
Aortic valve
- From:
Journal of Chinese Physician
2025;27(8):1125-1129
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the clinical effect of different types of aortic root replacement in adolescent patients with aortic root aneurysm by analyzing the perioperative and follow-up conditions of surgical treatment for adolescent aortic root aneurysm.Methods:The clinical data of patients aged ≤18 years who were admitted to the Beijing Anzhen Hospital from November 2012 to February 2025, diagnosed with aortic root aneurysm by ultrasound or aortic computed tomography angiography (CTA) and requiring surgical intervention, were collected retrospectively. They were divided into the valve-sparing aortic root replacement group (David operation group) and the aortic root replacement group (Bentall operation group) according to the surgical method. The perioperative results and long-term follow-up results of the two groups were analyzed. Kaplan-Meier survival curves were drawn to compare the reoperation intervention rate between the two groups.Results:A total of 25 patients were included in this study, including 17 in the Bentall group and 8 in the David group. There were no statistically significant differences in gender, age, blood routine, liver and kidney function, coagulation function, and electrolyte internal environment between the two groups (all P>0.05). There were no statistically significant differences in operation time and intensive care unit stay between the two groups (all P>0.05). Compared with the Bentall operation group, the intraoperative blood loss in the David operation group was more ( P<0.05). During the follow-up, no reoperation occurred in the Bentall operation group, while 3 patients in the David operation group had long-term re-intervention. The long-term reoperation intervention rate in the David operation group was higher than that in the Bentall group ( P=0.042), but there was no statistically significant difference in the aortic valve-related surgical intervention rate between the two groups ( P=0.15). Conclusions:For adolescent patients with aortic root aneurysm, although David operation may face long-term reoperation intervention, this intervention may not be due to the difference in surgical methods. Both Bentall operation and David operation are safe and reliable, with good perioperative results and stable medium and long-term prognosis.
