Bibliometric study on the application of microRNAs for axonal regeneration after peripheral nerve injury
10.16557/j.cnki.1000-7547.2025.01.012
- VernacularTitle:微RNA在周围神经损伤后轴突再生中的作用的文献计量学研究
- Author:
KUTILUKE·SHOUKEER
1
;
AIKEBAIERJIANG·AISAITI
1
;
SHALAYIDING·AIERXIDING
1
;
AIKEREMUJIANG·MUHEREMU
1
Author Information
1. 新疆医科大学第六附属医院骨科,乌鲁木齐 830002
- Publication Type:Journal Article
- Keywords:
peripheral nerve injury(PNI);
microRNA;
axon regeneration;
bibliometry;
peripheral nerve regener-ation;
visual analysis
- From:
Chinese Journal of Neuroanatomy
2025;41(1):80-88
- CountryChina
- Language:Chinese
-
Abstract:
Objective:Peripheral nerve injury(PNI)is the most common clinical condition.In this study,the current hotspot and future trends of the therapeutic role of microRNA(miRNA)in posterior axon regeneration were evaluated,through bibliometric analysis of peripheral nerves,to provide a reliable reference for later related studies.Methods:Published data from 2009 to 2024 were collected from the Web of Science database by key words TS=mi-croRNA OR TS=miRNA AND TS=peripheral nerve injury OR TS=microRNA OR TS=miRNA AND TS=axonal re-generation screening.The visualization analysis software CiteSpace was used to evaluate the author,country,keywords,outbreak words,institutions,etc.Results:A total of 301 documents were retrieved from the Web of Science database,and 288 documents finally fit the study post eliminating and screening.The 288 articles used in this study have a total of 1513 authors from 34 countries,and 1513 authors from 358 institutions published in 148 journals,citing 13941 articles from 2038 journals.In addition,this study lists the top 5 authors of the annual publication,national distribution,5 arti-cles with the most cited times and the top ten institutions of articles.Moreover,among them,China is the country with the largest number of articles,but there is still a significant gap in the quality of articles when compared with European and American regions.The analysis of institutions found that domestic institutions account for the largest proportion of the research in this field,with close mutual cooperation,but lack of cooperation with foreign institutions.The most cited article in research is"Let-7 microRNAs Regenerate Peripheral Nerve Regeneration by Targeting Nerve Growth Factor"which was cited 34 times.The institution with the largest publication volume is 31 articles from Nantong University.Conclusion:Although the research on therapeutic role of tiny RNA in axon regeneration after peripheral nerve injury started late,the number of papers is relatively small,but it has great potential.As the most popular topic today,tiny RNA has been inuetigated regarding its mechanistic action in the fields of nerve inflammation,nerve cell repair and re-generation,neuroprotection and functional recovery.With the investment in scientific research in this field,more high-quality articles will be published in excellent journals at home and abroad,ushering in a new era in the treatment of pe-ripheral nerve injury.
