Research progress on relationship between vitiligo and metabolic disease
10.3969/j.issn.1000-484X.2025.03.045
- VernacularTitle:白癜风与代谢性疾病发病机制的相关性研究
- Author:
Jingyi SHI
1
;
Hongjuan WANG
1
;
Xiaojing KANG
1
Author Information
1. 新疆维吾尔自治区人民医院皮肤性病科,新疆皮肤病临床医学研究中心,新疆皮肤病研究重点实验室,乌鲁木齐 830001
- Publication Type:Journal Article
- Keywords:
Vitiligo;
Metabolic diseases;
Diabetes;
Hyperlipidemia;
Hypertension
- From:
Chinese Journal of Immunology
2025;41(3):767-770
- CountryChina
- Language:Chinese
-
Abstract:
Vitiligo is an acquired depigmentation skin disease characterized by depigmentation patches formed by the loss of epidermal melanocytes,which seriously affects the physical and mental health of patients.The pathogenesis of vitiligo has not yet been elucidated,mainly related to factors such as genetics,oxidative stress,autoimmunity,inflammatory response,and neurotransmitters.In recent years,with the in-depth study of the pathogenesis of vitiligo and the improvement of epidemiological data,some scholars be-lieve that vitiligo is not only a skin disease that affects beauty,but also may be related to metabolic disorders.Vitiligo is often accompa-nied by metabolic diseases such as obesity,dyslipidemia,abnormal glucose tolerance,diabetes and hypertension.Vitiligo patients with metabolic diseases limit their treatment options,increase the risk of drug interactions,and even increase mortality.At present,the pathogenesis of metabolic diseases in vitiligo patients is not clear.This article reviews the relationship between vitiligo and metabol-ic diseases,which can help in early clinical diagnosis and prevent the occurrence of metabolic diseases.
