Advances in Helicobacter pylori Infection-negative Gastric Cancer
10.3969/j.issn.1008-7125.2024.07.009
- VernacularTitle:幽门螺杆菌感染阴性胃癌的研究进展
- Author:
Qianqian SHI
1
;
Xiaoyun WANG
;
Ruyi WANG
Author Information
1. 江南大学附属中心医院(无锡市第二人民医院)消化内科(214002);南通大学无锡临床学院
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori;
Stomach Neoplasms;
Pathogenesis
- From:
Chinese Journal of Gastroenterology
2024;29(7):433-436
- CountryChina
- Language:Chinese
-
Abstract:
Gastric cancer ranks as the third leading cause of cancer-related mortality globally.Helicobacter pylori infection-negative gastric cancer(HPINGC),accounting for 0.42%-5.4%of all gastric cancer cases,has received limited research attention.In recent years,with the promotion of Helicobacter pylori eradication,the proportion of HPINGC in gastric cancer has shown a progressive rise,and the exploration of its pathological characteristics and pathogenesis has become an urgent issue to be solved.Based on its histopathological characteristics,HPINGC can be classified into five types:gastric adenocarcinoma of fundic gland type,gastric foveolar type adenocarcinoma,intestinal type adenocarcinoma,pure signet-ring cell carcinoma,and pyloric gland type adenocarcinoma.This article reviewed the advances in characteristics and pathogenesis of different types of HPINGC,offering new perspectives for further exploration of treatment strategies.
