Research Progress of Non-enterotoxigenic Bacteroides fragilis in Colitis
10.3969/j.issn.1008-7125.2024.07.006
- VernacularTitle:非产肠毒素型脆弱拟杆菌在结肠炎中的研究进展
- Author:
Yue YUAN
1
;
Qiuyue HE
;
Yinglei MIAO
Author Information
1. 昆明医科大学第一附属医院消化内科(650032)
- Publication Type:Journal Article
- Keywords:
Non-Enterotoxigenic Bacteroides fragilis;
Intestinal Flora;
Colitis;
Next-Generation Probiotics
- From:
Chinese Journal of Gastroenterology
2024;29(7):414-418
- CountryChina
- Language:Chinese
-
Abstract:
The gut microbiota is closely related to the occurrence and development of colitis.Enterotoxigenic Bacteroides fragilis secretes enterotoxins,which can stimulate the body to induce colitis,while the type Ⅵ secretion system and antimicrobial proteins of non-enterotoxigenic Bacteroides fragilis are engaged in competition among the Bacteroides.The bacterial products of non-enterotoxigenic Bacteroides fragilis,such as polysaccharide A,short-chain fatty acids,and α-galactosylceramide,can mediate beneficial interactions with the host.This article reviewed the biological characteristics of non-enterotoxigenic Bacteroides fragilis and its mechanism of action in colitis,with the aim of providing theoretical basis for its future clinical application as a probiotics.
