Research progress on pathological detection method,result interpretation and ex-pression of Claudin18.2 protein in malignant solid tumors
10.13315/j.cnki.cjcep.2025.06.013
- VernacularTitle:Claudin18.2蛋白的病理学检测方法、结果判读及其在恶性实体肿瘤中表达的研究进展
- Author:
Qinlu LI
1
;
Yu ZHOU
1
;
Zijian LU
1
;
Dan JIANG
1
Author Information
1. 四川大学华西医院病理科,成都 610041;四川大学华西医院临床医学院,成都 610041
- Publication Type:Journal Article
- Keywords:
malignant solid tumors;
Claudin18.2;
detection method;
interpretation criteria
- From:
Chinese Journal of Clinical and Experimental Pathology
2025;41(6):776-781
- CountryChina
- Language:Chinese
-
Abstract:
Claudin18.2 is a member of the tight junction protein family,which can be abnormally expressed in a variety of malignant solid tumors,including gastric cancer.The drug therapy targeting Claudin18.2 has been a hot top-ic in recent years,making Claudin18.2 protein detection an important means of screening for tumor therapy.In this re-view,the clinical pathological detection methods,interpretation criteria,and expression research status of Claudin18.2 protein in various malignant solid tumors are reviewed,aiming to provide new ideas for tumor detection and treatment based on Claudin18.2 protein.
