Quality Evaluation of Randomized Controlled Trials of Exercise Therapy of Traditional Chinese Medicine for Parkinson's Disease
10.11969/j.issn.1673-548X.2025.05.028
- VernacularTitle:中医运动疗法对帕金森病临床效果随机对照试验的质量评价
- Author:
Weili ZHANG
1
;
Jing YANG
;
Yiqing CAI
Author Information
1. 102488 北京中医药大学生命科学学院整合医学中心
- Publication Type:Journal Article
- Keywords:
Parkinson's disease;
Exercise therapy of traditional Chinese medicine;
RCT;
Quality evaluation;
CONSORT
- From:
Journal of Medical Research
2025;54(5):158-165
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the methodological and report quality of the randomized controlled trials(RCT)of Traditional Chinese Medicine(TCM)exercise in patients with Parkinson's disease(PD).Know the current quality status and existing problems,and provide reference for future clinical practice.Methods After Chinese and English databases were searched by computer.We referred to Cochrane 5.1.0 Bias Risk Assessment Tool and the CONSORT 2010 Statement,evaluated the methodology and report quality of the in-cluded RCT.Results 54studies were included,57.4％were Tai chi intervention,the concealment of randomization and allocation schemes,blinding of outcome assessors,and other sources of bias were not adequately reported.96.3％(52studies)had a high risk of blinding subjects and intervenors,only 14.8％(8studies)used and described the concealment of randomization,and 38.9％(21 studies)reported the use of blinding of outcome assessors.The evaluation results of CONSORT statement showed that in total 37subitems,5subitems(13.5％)had a report rate of 0.More than half of the subitems(67.6％)had a report rate of less than 50％,in-cluding concealment of allocation(14.8％),implementation of blinding(38.9％),sample-size estimation(16.7％),intention-to-treat analysis(20.4％),and protocol registration(22.2％),etc.Conclusion The methodological and report quality of RCT were low.In the future,researchers should strictly follow the CONSORT statement to standardize the design,implementation and reporting of RCT,improve the higher methodological quality and pay more attention to outcomes in non-motor function and safety outcomes,then provide o-riginal studies with better quality for PD management and promote them to be transformed and utilized.Finally,promote exercise therapy of traditional Chinese medicine in PD management.
