The relationship between physical activity and blood pressure in patients with type 2 diabetes mellitus under different hemoglobin glycation index levels
10.3969/j.issn.1000-6710.2025.01.003
- VernacularTitle:不同糖化血红蛋白变异指数水平下2型糖尿病患者的体力活动与血压的关系探究
- Author:
Haodong TIAN
1
;
Haowei LIU
1
;
Hanglin YU
1
;
Li PENG
1
Author Information
1. 西南大学体育学院(重庆 400715);国家体育总局体质评价与运动机能监控重点实验室(重庆 400715)
- Publication Type:Journal Article
- Keywords:
type 2 diabetes;
hemoglobin glycation index;
blood pressure;
physical activity
- From:
Chinese Journal of Sports Medicine
2025;44(1):22-28
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between physical activity(PA)and blood pressure(BP)in patients with type 2 diabetes mellitus(T2DM)under different levels of hemoglobin glycosylat-ed index(HGI).Methods Totally 469 T2DM patients(male/female:235/234;those no less than 60 years old/more than 60:169/300)were randomly recruited from a class-2 grade-A hospital for a physi-cal examination and surveyed using the International Physical Activity Questionnaire(IPAQ).Then HGI was calculated based on glycosylated hemoglobin(HbA1c)and fasting plasma glucose(FPG),and the correlations of HGI to PA and BP were analyzed.Patients were divided into a low HGI group(L-G,HGI≤-0.13%)and a high HGI group(H-G,HGI>-0.12%)using the median split meth-od,and their differences in BP and PA were analyzed.Moreover,the patients in each group were fur-ther divided into low,moderate,and high PA levels based on the IPAQ,and their differences in BP were compared.Results The systolic and diastolic blood pressures(DBP)were of significantly positive correlation with HGI(P<0.01),while PA was of significantly negative correlation with HGI(P<0.05),without significant association between BP and PA.Moreover,the H-G group had significantly higher BP but significantly lower total PA than the L-G group.In the H-G group,DBP increased sig-nificantly with the increase of PA(P<0.01),while in the L-G group,BP decreased significantly with it(P<0.05).Conclusion HGI is closely related to BP control in T2DM patients,and may play an im-portant mediating role in the regulation of BP by PA.Moreover,patients with low HGI levels can take higher-intensity PA to control BP,while those with high HGI levels should be cautious in choos-ing exercise intensity and avoid high-intensity PA.