Research progress of new drugs for advanced gastrointestinal stromal tumors in clinical practice
10.3969/j.issn.1005-6483.20250600
- VernacularTitle:晚期胃肠间质瘤临床新药研究进展
- Author:
Xuefeng ZHAO
1
;
Fei LIU
1
;
Yong LI
1
Author Information
1. 050011 河北石家庄,河北医科大学第四医院外三科
- Publication Type:Journal Article
- Keywords:
gastrointestinal stromal tumors;
drug therapy;
research progress
- From:
Journal of Clinical Surgery
2025;33(6):665-668
- CountryChina
- Language:Chinese
-
Abstract:
Drug therapy is the main treatment for advanced gastrointestinal stromal tumors.Tyrosine kinase inhibitors targeting KIT/PDGFRA have significant efficacy.However,the problem of primary/induced drug resistance has promoted the development of new drugs to improve the treatment effect of the disease,and drugs with new targets/mechanisms of action are also being developed continuously.This article provides an overview of the recent progress in drug therapy research in this field.