Follow-up analysis of blood vessel regeneration in young permanent teeth of patients with pulp necrosis using platelet-rich fibrin
10.13591/j.cnki.kqyx.2025.03.003
- VernacularTitle:富血小板纤维蛋白用于牙髓坏死的年轻恒牙患儿血管再生情况的随访分析
- Author:
MAIMAITIYIMING MAIBUBAIMU
1
;
AISAITI MAYINUER
1
;
PAERHATI PAWUZIYE
1
;
AMUTI RIZIWAGULI
1
Author Information
1. 新疆维吾尔自治区人民医院口腔科,新疆乌鲁木齐(830001)
- Publication Type:Journal Article
- Keywords:
platelet rich fibrin;
young permanent tooth;
pulp necrosis;
pulp regeneration surgery
- From:
STOMATOLOGY
2025;45(3):175-179,184
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the therapeutic effect of injectable plateletrich fibrin(i-PRF)as a scaffold for pulp regeneration surgery in young permanent teeth with pulp necrosis.Methods Sixty young children with permanent tooth pulp necrosis who underwent pulp regeneration surgery in the Department of Stomatology of our hospital from March 2021 to October 2022 were included.The differ-entiation between the i-PRF group(33 cases)and the blood clot group(27 cases)was based on the different scaffold materials used dur-ing the treatment process.Follow up for 1 year,cone beam CT(CBCT)was used to measure the apical foramen diameter,dentin wall thickness,root length,root canal area,and root area of the affected tooth before treatment,at 3,6,9 and 12 months of treatment.The increase in root length,increase in dentin wall thickness,decrease in apical foramen diameter,increase in root area,decrease in root canal area,and clinical data between the two groups of patients before and after treatment were compared.The tooth color,pulp vitali-ty,and tooth eruption height of two groups of patients were recorded before and after treatment.Results At 9 and 12 months post sur-gery follow-up,the root length,dentin wall thickness,and root area of the i-PRF group were higher than those of the blood clot group(P＜0.05).According to the results of the last follow-up,it was calculated that the increase in root length,dentin wall thickness,and root area in the i-PRF group were higher than those in the blood clot group,and the differences were statistically significant(P＜0.05).There was no statistically significant difference in the changes in tooth color,positive pulp vitality,and eruption height between the two groups of patients(P＞0.05).Conclusion The use of blood clots and i-PRF as scaffolds for pulp regeneration in the treatment of young permanent tooth pulp necrosis has been proven to be effective,but the use of i-PRF as a scaffold is more effective in promoting root growth and increasing dentin wall thickness.
