Study of the characteristics of CT vessel and myocardial perfusion in patients with ischemia with non-obstructive coronary artery disease
10.3969/j.issn.1002-1671.2025.04.012
- VernacularTitle:缺血伴非阻塞性冠状动脉疾病的CT血管及心肌灌注影像特征研究
- Author:
Jingji XU
1
;
Xing QIN
Author Information
1. 空军军医大学西京医院放射诊断科,陕西 西安 710032
- Publication Type:Journal Article
- Keywords:
coronary computed tomography angiography;
computed tomography myocardial perfusion imaging;
ischemia with non-obstructive coronary artery disease
- From:
Journal of Practical Radiology
2025;41(4):594-598
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the characteristics of computed tomography myocardial perfusion imaging(CT-MPI)and coronary computed tomography angiography(CCTA)in patients with ischemia with non-obstructive coronary artery disease(INOCA).Methods A total of 214 patients with coronary heart disease who underwent CT-MPI and CCTA for angina pectoris were retrospectively selected.Based on the results of CCTA and CT-MPI,all patients were divided into intermediate INOCA(n=124),INOCA(n=28)and obstructive coronary artery disease(CAD)(n=62)groups.The CCTA characteristics and CT-MPI features of all patients were analyzed,respectively.Multigroup analysis used one-way analysis of variance or Kruskal-Wallis H test.Results INOCA group had shorter plaque length than obstructive CAD group(P=0.005),while no difference was detected in high-risk plaque between the two groups.INOCA group had higher abnormal myocardium volume(P=0.002)and higher abnormal myocardium volume ratio(P＜0.001)than obstructive CAD group.Compared with INOCA group,intermediate INOCA group had higher global myocardial blood flow(MBF)(P＜0.001),lower abnormal myocardium volume and volume ratio(P＜0.001,P＜0.001)and abnormal myocardium segments ratio(P=0.009).Conclusion Patients with INOCA and obstructive CAD have different characteristics of CT-MPI and CCTA,the intermediate INOCA might be the earlier stage of INOCA.
