CT and MRI findings of giant cell reparative granuloma in lateral skull base
10.3969/j.issn.1002-1671.2025.04.005
- VernacularTitle:侧颅底巨细胞修复性肉芽肿CT及MRI表现分析
- Author:
Pengfeng SUN
1
;
Jiping DONG
1
;
Xiaoping WU
1
;
Xiangchun YANG
1
;
Caixia PEI
1
;
Hongsheng LIU
1
;
Run LIU
1
Author Information
1. 西安交通大学附属西安市中心医院放射科,陕西 西安 710003
- Publication Type:Journal Article
- Keywords:
giant cell reparative granuloma;
lateral skull base;
computed tomography;
magnetic resonance imaging
- From:
Journal of Practical Radiology
2025;41(4):560-563
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the CT and MRI features of giant cell reparative granuloma(GCRG)in lateral skull base.Methods The CT,MRI and clinicopathological data of 8 patients with GCRG in lateral skull base were collected and analyzed.Results All of the eight lesions were unilateral and solitary(three on the left side and five on the right side),with widespread involvement affecting two or more bony structures of the lateral skull base.All lesions showed expansile and lytic bone destruction on CT scans,the margins were clear(7/8),and the sclerotic changes could be seen at the margin of all eight lesions.On MRI,the lesions revealed heterogeneous isointense and hypointense on T1WI,and heterogeneous hypointense with focal cystic changes on T2WI,without fluid-fluid levels.The enhanced scan showed heterogeneous enhancement.Seven cases extended to the middle cranial fossa,caused com-pression of the temporal lobe brain tissue,with thickened and strengthened adjacent meninges.Conclusion The GCRG in lateral skull base has certain characteristic appearances on CT and MRI;understanding these characteristic manifestations can provide a basis for accurate diagnosis.
