Progress on immune mechanism of avian infectious bronchitis

VernacularTitle:禽传染性支气管炎病毒免疫机制的研究进展
Author: Yang LI ¹ ; Aili FAN ; Jilin CHEN ; Lina DONG ; Zonghui ZUO ; Shuhui MA ; Gang XU
Author Information

1. 天津农学院动物科学与动物医学学院天津市农业动物繁育与健康养殖重点实验室,天津 300392
Publication Type:Journal Article
Keywords: avian infectious bronchitis virus; immune response; molecular mechanisms
From: Chinese Journal of Veterinary Science 2025;45(3):619-626
CountryChina
Language:Chinese
Abstract: Avian infectious bronchitis(IB),a rapidly spreading and acute disease in chickens,is caused by the infectious bronchitis virus(IBV).IB is characterized by its remarkable genetic varia-bility.IBV has a high degree of mutation,and the existing means of immunization often fail to a-chieve good results,seriously affecting the development of the domestic poultry industry.This ar-ticle offers a comprehensive review of the current understanding of the immune response to IBV,focusing on three key areas:non-specific immunity,mucosal immunity,and specific immunity.By dissecting these aspects,the aim is to provide a theoretical reference for the study of the immune mechanism of IBV.