Cortical functional mechanism of impaired postural control in patients with chronic low back pain:a fNIRS study
10.3969/j.issn.1001-1242.2025.05.003
- VernacularTitle:基于近红外脑功能成像技术的慢性腰痛患者姿势控制受损的皮质功能机制研究
- Author:
Hongjiang WANG
1
;
Xin LIU
;
Guifang ZHANG
Author Information
1. 中山大学附属第一医院康复医学科,广州市,510080
- Publication Type:Journal Article
- Keywords:
chronic low back pain;
postural control;
functional near-infrared spectroscopy;
oxygenated hemo-globin concentration;
functional connection
- From:
Chinese Journal of Rehabilitation Medicine
2025;40(5):661-672
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore whether the function of the cerebral cortex changes during postural control tasks in pa-tients with chronic low back pain(CLBP),from a central perspective by using near-infrared functional brain imaging(fNIRS)technology,and to provide new ideas for elucidating the pathogenesis of CLBP.Method:Tecno-body and fNIRS were used to examine the displacement of the center of pressure,as well as the changes in HbO,HbR and HbT concentrations and functional connectivity of the cortical ROI in the pa-tients with CLBP(n=30)and the healthy subjects(n=25)during four different standing tasks..Result:Compared to the HC group:①The COP displacement area of subjects in the CLBP groups was significant-ly increased during the four different static standing tasks(P<0.05);②During the standing tasks,the activation de-grees of M1,PSC,DLPFC and PFC in the CLBP group were significantly different from that of the healthy control group(P<0.05).③The functional connectivity in some ROI areas also significantly changed(P<0.05).Conclusion:Compared to the age-matched healthy people,the CLBP patients had significantly reduced postural control ability during static standing;meanwhile,the activation and functional connectivity of PSC,M1,DLP-FC and PFC were changed in different degrees.These findings indicate that the changes in sensory and motor cortex function may be one of the causes of postural control impairment in patients with CLBP.
