Effect of cognitive-motor dual-task training in patients with subacute stroke:study with functional near-infrared spectroscopy
10.3969/j.issn.1001-1242.2025.06.014
- VernacularTitle:认知运动双任务训练对亚急性期卒中患者疗效的功能性近红外光谱成像研究
- Author:
Renlong ZHOU
1
;
Xiang LI
1
;
Hongrui ZHANG
1
Author Information
1. 济宁医学院附属医院康复医学科,山东省 济宁市,272000
- Publication Type:Journal Article
- Keywords:
cognitive-motor dual-task;
stroke;
cognitive function;
motor function;
functional near-infrared spectroscopy
- From:
Chinese Journal of Rehabilitation Medicine
2025;40(6):894-899,908
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the effect of cognitive-motor dual-task training on patients with subacute stroke and to analyze the mechanism of improvement in brain functional connectivity by functional near-infrared spectroscopy(fNIRS).Method:Forty patients with subacute stroke were randomly divided into a control group(n=20)and an obser-vation group(n=20).All patients were given conventional comprehensive rehabilitation treatment.The control group was given walking and cognitive function training separately,while the observation group was given cog-nitive-motor dual-task training.The cognition,motor function and activities of daily living were evaluated by mini-mental state examination(MMSE),functional ambulation category scale(FAC)and modified Barthel in-dex(MBI)before and after 6 weeks of treatment.fNIRS was used to compare the functional activity of the primary motor cortex(M1),supplementary motor area(SMA),prefrontal cortex(PFC)and the functional connectivity of each brain region under task states.Result:A total of 37 patients were included in the final statistics,and there was no difference in baseline lev-el between the two groups before treatment(P>0.05).After intervention,the MMSE,FAC and MBI of the two groups were better than those before treatment,and the observation group was better than the control group.The differences were statistically significant(P<0.05).At the same time,fNIRS observation showed that after treatment,except the right M1 and right PFC,the functional intensity of M1,SMA and PFC in the two groups were higher than those before treatment.The functional intensity of SMA in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).Af-ter treatment,the functional connection intensity of brain regions on the injured side in the two groups were higher than those before treatment,and the functional connection intensity between bilateral SMA,M1 and PFC,SMA and PFC in the observation group were higher than those in the control group,and the differenc-es were statistically significant(P<0.05).Conclusion:Compared with conventional motor and cognitive function training,cognitive-motor dual-task training can more significantly improve cognitive,motor function and independence in patients with subacute stroke.The mechanism may be related to the fact that dual-task training can effectively improve the brain func-tional intensity of the SMA area,the functional connection intensity between M1 and PFC as well as SMA and PFC.
