Advances in pharmacokinetics of isavuconazole in special population
10.12092/j.issn.1009-2501.2025.05.016
- VernacularTitle:艾沙康唑特殊人群药代动力学研究进展
- Author:
Jingxian XIE
1
;
Jianjun DU
;
Lu CHEN
;
Lijuan ZHANG
;
Yong YANG
Author Information
1. 西南医科大学药学院,泸州 646000,四川;四川省医学科学院四川省人民医院/电子科技大学医学院,个体化药物治疗四川省重点实验室,成都 610072,四川
- Publication Type:Journal Article
- Keywords:
isavuconazole;
special populations;
pharmacokinetics
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2025;30(5):709-713
- CountryChina
- Language:Chinese
-
Abstract:
Isavuconazole represents a novel gen-eration of triazole antifungal agents for the treat-ment of invasive trichothecenes in adults.The phar-macokinetic profile of isavuconazole differs in spe-cial populations,including children,patients with ex-tracorporeal membrane oxygenation,those with he-patic or renal injury,patients undergoing blood puri-fication,and critically ill individuals and solid organ transplant recipients.These differences impact the safety and efficacy of patient treatment.This article presents the latest progress in the pharmacokinetic study of isavuconazole in these special populations.
