Surface disinfection efficacy of 254 nm continuous ultraviolet and pulsed ultraviolet laser
10.12138/j.issn.1671-9638.20256933
- VernacularTitle:254 nm连续紫外线与脉冲紫外激光物体表面消毒研究
- Author:
Jie ZHAO
1
;
Lei ZHAO
1
;
Yiran SHANG
1
;
Jinhui WU
1
;
Ying YI
1
;
Cheng DENG
1
;
Jiancheng QI
1
;
Zongxing ZHANG
1
Author Information
1. 军事科学院系统工程研究院,国家生物防护装备工程技术研究中心,天津 300161
- Publication Type:Journal Article
- Keywords:
ultraviolet;
pulsed ultraviolet laser;
continuous ultraviolet;
disinfection;
sterilization;
logarithmic killing value
- From:
Chinese Journal of Infection Control
2025;24(3):316-322
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare and analyze the germicidal efficacy of continuous ultraviolet and pulsed ultravio-let(UV)lasers on pathogenic microorganisms.Methods Spore slides of Escherichia coli and Bacillus atrophaeus were irradiated using a 254 nm ultraviolet mercury lamp and UV laser.The carrier quantitative germicidal test was conducted to determine the disinfection efficacy at different irradiation doses.Results When the irradiation dose of the ultraviolet mercury lamp was 245.52 mJ/cm2,the logarithmic killing values of Escherichia coli and Bacillus atro-phaeus spores were 5.00 and 2.92,respectively,and the mean logarithmic killing doses were 49.10 and 84.08 mJ/cm2,respectively;When the UV laser irradiation doses were 208.39 and 206.80 mJ/cm2,the logarithmic killing values for the two microorganisms were 6.29 and 3.32,respectively,and the mean logarithmic killing doses were 33.13 and 62.29 mJ/cm2,respectively.Conclusion Compared with continuous UV radiation,pulsed UV laser has stron-ger penetration ability,better killing efficacy on pathogenic microorganisms at the same radiation dose,and can con-duct targeted disinfection and sterilization on the surface of objects directionally.
